Estimation of target proteins achieved in critically ill patients receiving enteral nutrition (EN) and its impact on clinical outcomes

BACKGROUND

Critical ill patients are susceptible to protein catabolism associated with increased morbidity. This study assesses the target proteins achieved in patients receiving EN & its effect on clinical outcomes in the critically ill.

METHODS

Retrospective study conducted between January to December 2014 in the ICU of a tertiary care hospital. 47 adult patients in ICU receiving EN for > 3 days were included. The patients were categorized according to percentage of target proteins achieved (Group A >75% & B <75%). Baseline demographics, nutritional status and EN practice parameters were collected and analysed. The length of stay (LOS), ventilator free days and mortality in ICU were evaluated. RESULTS AND DISCUSSION Patients’ mean age was 63 ± 14.8y & body mass index 24.4±4.9. Subjective global assessment revealed that 30(64%) were moderately malnourished & 2(4%) were severely malnourished. An average of 88% & 59% target proteins was achieved in Groups A & B. The average target proteins achieved on the 3rd day was 78% and 50% on the 7th day for Group A. For Group B average target proteins achieved was 56% & 36% on the 3rd & 7th days. Mean feed interruption hours increased to 12.2hours by 7th day. Group B had a higher mean feed initiation time 33.2±40.3hours & interruptions of 35.1±47.5hours when compared with Group A (17.85±29.7 & 11.8±12.7hours). Average LOS & ventilator free days in ICU was less in the Group A (13.9±8.1 & 9.1±7.9). Mortality of 32% observed in Group B where percentage of proteins achieved was least. CONCLUSION Protein metabolism disturbances due to body’s evolutionary metabolic response is observed in the critically ill & negative protein balance secondary to severe disease is associated with poor clinical outcomes. Provision of optimal proteins mitigates protein loss & maybe associated with reduced LOS & mortality in the ICU & thereby improved health care costs.

Anthropometric measurements – Perception vs Reality

Background

Understanding the role of anthropometric measurements is important for maintaining good health and avoiding obesity and malnutrition related medical problems. The purpose of this study was to evaluate the understanding of common anthropometric measurements such as height, weight and waist measurements among adults in an outpatient clinic by comparing their perceived and actual measurements.

Methods

A prospective, non-interventional study conducted in a free standing outpatient clinic from December 2014 to April 2015. All patients and attendants who consented to participate were included. Additionally volunteering healthcare professionals were included to compare perception of healthcare professionals with the non-medical general public. Participants were requested to complete a questionnaire with demographic information such as age, gender and occupation. In addition they were requested to document perceived anthropometric measurements and perceived level of physical fitness. They were also asked their opinion on importance of checking weight and their satisfaction about their current weight. Their actual height, weight and waist measurements were then measured and compared with their perceived measurements using Bland-Altman plots.

Results and Discussion

The study included 185 subjects (120M/65F; mean age–45.12?13.8; 59 healthcare professionals and 126 others). 85.4% of participants were confident about their weight, 71.9% of their height and 27.02% of their waist measurements. Participants underestimated their weight and waist measurement and overestimated their height. Mean differences for weight, height and waist measurements were 2.15kg, -0.18cm and 2 inches respectively. Range of agreement were (95%CI 6.71-11.03) for weight, (95%CI 8.07-8.44) for height and (95%CI 7.53-3.51) for waist measurement. Range of agreement was wide in both healthcare and non-healthcare groups (CI -6.73-4.95 and 10.48-7.81 respectively). On perceived fitness, 16.6% perceived themselves as excellently fit, 54.59% as above average, 7.5% as average and 21.6% as not fit. 87% participants (93.2% healthcare professionals) felt checking weight was important. 51.3% participants were unhappy with their weight, with a positive correlation between unhealthy BMI status and dissatisfaction.

Conclusion

In our study, a discrepancy existed between the actual and perceived anthropometric measurements of participants, irrespective of profession. Participants were generally more aware of their heights and weights than waist measurement. Participants with unhealthy BMI scores were more dissatisfied with their weight status.

APPLICATION OF THREE DIFFERENT TOOLS ON NUTRITION-RISK SCORING IN THE INTENSIVE CARE UNIT

Background

Nutrition status screening, assessment and monitoring is essential in the critically ill to reduce morbidity and mortality. Identifying patients’ at risk of malnutrition is usually difficult due to the nature of illness. Traditional screening methods are thought to be often limited due to their subjective nature. Purpose of this study is to determine the correlation of 3 different nutrition screening tools to classify the time consumed in identifying the risk of malnutrition.

Method

A sample of 44 patients expected to stay >24 hrs in ICU were assessed using the institution’s routine nutrition screening method; Subjective Global Assessment (SGA) & the NUTrition Risk in Critically ill (NUTRIC) score (age, APACHE II, SOFA, number of comorbidties, and days from hospital to ICU admission). Biochemical parameters, nutrient delivery, average length of stay (ALOS) in the ICU were also noted. GOS (Glasgow Outcome Scale) & Karnofsky performance status scale were the outcome scales used. Descriptive statistics & bivariate correlation were the statistical methods utilized.

Results

At risk of malnutrition was observed in 31.8% (n=14) using SGA, 27.3% (n=12) routine nutrition screening & 27.3% (n=12) NUTRIC score. There was significant correlation between all three tools (?*=0.05). Standard ALOS of <4.5 days (ICU) was seen in 18.2 %. Nutrient delivery of >75% was achieved among 72.7%. Only 6.8% had significant GOS (score 5) & 2.3% met the karnofsky performance status outcome (score 100).Time taken to complete routine nutrition screening, SGA & NUTRIC score, on an average was (approximately) 5, 7 and 15 minutes respectively.

Conclusion

On application of these tools, NUTRIC score is a more elaborate tool which includes various variables available in the ICU and is thought to be a superior score, by following it one may identify malnutrition appropriately. However the time taken for this new scoring system is higher. No significant difference in correlation was found between the traditional methods of nutrition screening and the NUTRIC score. Hence we had no added advantage of NUTRIC over traditional tools.

Nutrition Week – Knowledge Sharing Initiative – Key Learnings of AICNU 2015

As a part of nutrition week, participants from AICNU 2015 who are leaders in their respective fields have taken the initiative to share the knowledge from attending AICNU 2015 with those who could not. The first such knowledge sharing session is happening in Chennai.

Knowledge sharing initiative – Key Learnings of AICNU-2015

Date :         9-9-2015 , (Wednesday)

Time :         1.00 PM

Venue:      Harmony Hall,

The Residency

49, G.N. CHETTY ROAD,

T.NAGAR, CHENNAI-600 017. TEL; 28253434,

AGENDA
1.00 PM to 2.00 PM Lunch
TIME TOPIC SPEAKER
2.00pm Welcome Address Mr. Padmanabhan Sridharan ,

Regional Manager

Nestle Health Science, Chennai

2.15pm Targeted nutrition therapy can improve outcomes of cancer treatment Dr.Vinitha Krishnan,Phd,

Consultant Clinical Nutritionist,

Fortis Malar Hospital,

Chennai

 

2.30pm ABC of Paediatric ICU Nutrition

 

Ms. M.Bamini M.Sc ,RD
Chief Dietitian
Sundaram Medical Foundation, Chennai
2.45pm Nutritional management of patients with enterocutaneous fistula Ms. U. Uthara

Chief Dietitian
SIMS Hospital, Chennai

3.00pm Evolving concepts in Critical Care Nutrition Mr.P. Krishnamurthy

Senior Diet Counsellor

Vijaya Hospitals, Chennai

3.30pm Clinical Nutrition Quiz

Comparative study of the nutritional status of a geriatric population of an urban housing complex and an old age home

Comparative study of the nutritional status of a geriatric population of an urban housing complex and an old age home

Ms. B G Hazarika*, Ms. M Roy Chowdhury, Ms. S M Das

Department of Dietetics

Apollo Gleneagles Hospitals,Kolkata

Aim: To assess the nutritional status of a geriatric population in an urban community (kolkata).

Background: Elderly population contributed to 7% of total population of India in 2001and it will raise to 9% by 2016. In 2010,100 million people were aged above 60 years and by 2020 it will be 177 million. Ageing process is as such complex and multi-factorial. Chronic morbidities like diabetes and hypertension are becoming common health problems among the geriatric population.

Ageing is often accompanied by the occurrence of illness, which may increase the risk of nutritional deficiency. There is a need to compress the period of morbidity experienced by the elderly to minimize the occurrence of nutritional deficiency and improve well-being. Altered nutritional status is associated with the pathogenesis of a number of common diseases of the elderly. Thus it would appear that nutritional modulation represents one possible approach to successful ageing.

Method: Mini nutritional assessment (MNA) of Nestle Nutrition Institute was used to determine the screening score.

Results: Comparative scoring of the two facilities were surveyed. In the housing complex  about 55% female and 60% male were well nourished whereas in the old age home only about 5% of female and 7.28% of male were well nourished. 30% of female & 33% of male were at risk of malnourished in housing complex, whereas the percentage in the old age home was 33% & 92.8% respectively. Percentage of malnourished individuals in the housing complex was 15% for female & 7% for male. In the old age home mainly all the female population (62%) was malnourished.

Conclusion: Malnutrition prevailed among the members of the old age home. Psychological stress was common, which may be a factor of HTN. Sedentary lifestyle and over- eating may be a contributing factor towards the development of diabetes in the residence of the housing complex. In our study, the percentage of diabetes in housing complex and in old age home was 41% and 29% respectively, and that of hypertension it was 69% and 71%. It was observed that BMI above, 30 increased the prevalence of diabetes and hypertension. Counselling was done to improve the nutritional status of both the facilities. Continuous periodic contact sessions are carried out to bridge the nutritional gap and improve the quality of life of the geriatric population.

AICNU 2015 : Poster Presentation

The abstracts selected for poster presentation are as follows:

Poster No  Abstract ID  Research Abstracts Title  First Author
 1  AICNU2015-A46  Application of three different tools on Nutrition-Risk Scoring in the Intensive Care Unit  Ms. Srividya.N
2  AICNU2015-A27  Estimation of target proteins achieved in critically ill patients receiving enteral nutrition (EN) and its impact on clinical outcomes  Ms. S. Ramya
 3  AICNU2015-A22  Anthropometric measurements – Perception vs Reality  Ms. Hema Deenadayalan
 4  AICNU2015-A87  Does Hypocaloric feeding impact the outcome of critically Ill with increased BMI?  Ms. Vasumathi.M.M
 5  AICNU2015-A39  The ‘SUN’ Initiative: Do we have the scope to Scale Up Nutrition in the ICU?  Dr. Radha Reddy Chada
 6  AICNU2015-A90  Does Pre-Operative Nutritional Monitoring have an impact on Clinical Outcomes of Liver Transplantation?  Ms. Daphnee.D.K
 7  AICNU2015-A69  Feeding the critically ill: Is prone position a hinderance?  Ms. Rajalakshmi Parasuraman
 8  AICNU2015-A50  Role to assess the nutritional status and source and total protein intake with quality of life (FAACT score) in cancer patients  Ms. Divya S
 9  AICNU2015-A36  The Impact of Enteral Feed Interruption in Intensive Care Unit  Ms. V. Champa Mazumdar
 10  AICNU2015-A89  Analysis of Nutritional Deficits in Patients with End Stage Liver Disease (ESLD) Awaiting Liver Transplant  Ms. Daphnee.D.K
 11  AICNU2015-A91  Validation of a Nutritional Assessment Tool for Postoperative Paediatric Group  Dr.Vinitha Krishnan
 12  AICNU2015-A14  Food Habits of Our Future Generation  Ms. R. Anitha
 13  AICNU2015-A79  Minimal Hepatic Encephalopathy affects Nutritional Status and Health Related Quality of Life in patients with Chronic Liver Disease  Dr. Namita Panagaria
 14  AICNU2015-A18  Comparative study of potassium correction in hypokalemic patients using,IV,oral and dietary Potassium supplementation in critically ill patients  Ms. Ananya Konar
 15 AICNU2015-A38  A Prospective Study on Early Nutritional Intervention with Eicosa Pentonic Acid (EPA) in Head and Neck Cancer patient undergoing Radiotherapy Ms. Sharmila Sita.S
 16  AICNU2015-A3  Assessing Nutritional Status of patients with Blood Related Disorder and their Nutritional Management in a Tertiary Care Hospital in Odisha.  Ms.Sunita Sahoo
 17  AICNU2015-A98  Evaluation of Nutritional Support on the Growth Parameters of Preterm Infants  Ms. Gayathri.G
 18  AICNU2015-A96  Outcomes of Protocolised Nutritional Intervention in Severely Malnourished patients  Ms. Silvia Sargunam
 19 AICNU2015-A93  Impact of Nutrition intervention in critically ill patients Ms. Mahima. D
 20 AICNU2015-A88  Nutritional Status of the School Going Children  Ms. Divyalakshmi.K
 21 AICNU2015-A53  Cognitive Impairment Associated with Chemotherapy in Cancer Patients Ms. A.Rajeswari
 22  AICNU2015-A20  Impact of continuous training in improving knowledge & awareness of basic therapeutic nutrition among Inpatient food service boys  Ms. Champakamala.C
 23  AICNU2015-A11  Prevalence of Malnutrition and Nourishing the Little Hearts with Congenital Defects  Ms. Lekha. V.S
 24  AICNU2015-A5  To study the Improvement in PG-SGA Score of Oncology Patients through Nutritional Intervention  Ms. Anita Jatana
 25  AICNU2015-A68  BCAA Supplementation for Hepatic Encephalopathy Patients  Ms.V.Suganya
 26  AICNU2015-A58  Impact of nutritional counselling in head and neck cancer patients  Ms. Neelam Agarwal
 27  AICNU2015-A31  Assessment of Quality of Life among Dialysis patients  Ms. A Uma Maheswari
 28  AICNU2015-A12  Ketogenic Diet in Children with Refractory Epilepsy  Ms. Lekha. V.S
 29 AICNU2015-A74  Effect of domestic cooking on Polyphenol and antioxidant content in commonly consumed vegetables  Ms. Harsha Rao G
 30  AICNU2015-A71  EPA DHA enriched high protein supplementation increases weight among pre-operative dilated cardiomyopathy patients  Dr. Vinitha Krishnan
 31  AICNU2015-A97  Impact of regular patient follow up on weight loss and nutrient profile post bariatric surgery Ms. Ritika Samaddar
 32  AICNU2015-A95  Nutritional Status and its outcome in Heart and Lung transplant recipients-An overview  Ms. Rekha.S
 33 AICNU2015-A9  Comparative study on impact of dietary counseling and nutrient intervention on patients undergoing maintenance haemodialysis (thrice a week)  Ms. Rana S
 34  AICNU2015-A94  Assessment of Nutritional Status of patients (CKD on Hemodialysis) in Hospital and followed by nutritional intervention Ms. Vasundhara Padma
 35  AICNU2015-A86  A study on benefits of Nutrition Intervention in Oncology outpatients receiving Radiotherapy Ms.Vaishali Agarwal
 36  AICNU2015-A60  Effect of Dietary Interventions for Burns Patients  Sathish Lal
 37  AICNU2015-A29  To assess the impact of Medical Nutrition Therapy in Gestational Diabetes and monitor the blood glucose levels Ms.Rubina Begum
 38  AICNU2015-A82  Effect of Energy Intake on the Nutritional Status of Maintenance Haemodialysis (MHD) patients  Ms. D.Rekha
 39 AICNU2015-A78  Prevalence of hypercholesterolemia and dietary habits of presenting for preventive health check-up (PHC) program in a tertiary- care hospital  Ms. M.Malarkodi
 40 AICNU2015-A55  Pediatric York hill Malnutrition score (PYMS) in Pre and Post Bone Marrow Transplant Pediatric Patients  Ms. Bhuvaneswari B
 41 AICNU2015-A7  To study the Outcome of Nutritional Interventions on Long Stay Patient  Ms. Swati
 Poster No Abstract ID Clinical Case Vignets Title First Author
 1 AICNU2015-A49 2 year follow up on 2 case report on Low Arginine diet in Gyrate Atrophy  Ms. Harita shyam
 2 AICNU2015-A26  Management of Chylothorax in a post CABG patient- a case presentation  Ms. P Mallick
 3 AICNU2015-A80  Chyle Leak following Oesophagectomy – A Nutritional Challenge  Ms. Rajakumari
 4 AICNU2015-A8 Dietary Intervention for Propionic Acidemia  Ms. Swati
 5 AICNU2015-A6  Dietary intervention in case of Lymphangiectasia causing Protein Losing Enteropathy  Ms. Kanika Narang

Feasibility, safety, and outcome of very early enteral nutrition in critically ill patients

Background

In critically ill patients, early enteral nutrition (EN)within 24 to 72 hours is recommended. Although vasopressor-dependent shock after resuscitation is not a contraindication for EN initiation, feasibility and safety of very early (within 6 hours) EN initiation soon after resuscitation are unknown.

Objective
To evaluate the feasibility, safety, tolerance, and adequacy of very EN delivery in critically ill patients within 6 hours of intensive care unit (ICU) admission.

Material and methods

Prospectively collected data from a total of 308 medical and surgical patients admitted to the ICU for at least 3 days were analyzed. The patients in whom EN was initiated within 6 hours of ICU admission (n = 166) were compared with those in whom EN was initiated after 6 hours (n = 142). Comparisons were made between groups in the percentage of target calories and proteins delivered on day 3, percentages of patients achieving target calories and proteins on day 3, incidence of feed intolerance, ICU length of stay (LOS), hospital LOS, ICU/hospital discharge, and mortality.

Results

No significant differences were seen in percentage of calories (71.62% vs 71.83%; P = .09) and proteins (71.85% vs 68.89%; P = .2) delivered on day 3 between patients receiving EN within 6 hours and after 6 hours of admission. Similar number of patients achieved target calories (66.3% vs 67.6%; P = .8) and target proteins (66.9% vs 62.7%; P = .5) on day 3 in both groups. There were no significant differences between the groups for ICU LOS (11.41 days vs 11.72 days; P = .7) and hospital LOS (20.7 days vs 17.96 days; P = .1). A total of 77.1%
patients were discharged in the group in whom EN was initiated within 6 hours and 67.6% patients were discharged in the group where EN was initiated after 6 hours (P = .07). The mortality rate was 22.9% and 32.4%, respectively (P = .07), in these groups. Overall incidence of EN interruption was 20.13% without significant difference between the 2 groups (b6 hours, 16.2%; N6 hours, 24.7%; P = .087).

Conclusion

Initiation of EN within 6 hours of ICU admission is feasible and safe and can be implemented routinely in all ICU patients.

Patients’ attitude towards nutritional therapy in a comprehensive sleep clinic

Patients’ attitude towards nutritional therapy in a comprehensive sleep clinic: time for a wakeup call?

Ms. Hema Deenadayalan*, Ms. Lakshmi Ranganathan, Ms. Mary Isabel,
Dr. Nagarajan Ramakrishnan

Nithra Institute of Sleep Sciences, Chennai, India


Background:
Nutritional therapy is an integral component of patient care. Its goal is to aid the medical management with appropriate diet, thereby preventing complications from incorrect eating habits. Hence, it is important that, even in outpatient clinics, registered dietitians provide formal counselling and dietary treatment. It is also essential that patients understand the importance of diet treatment for compliance. The purpose of this study was to assess the attitudes of patients towards the dietary treatment in an outpatient setting.

Methods: This is a retrospective study done in a free standing outpatient Sleep clinic, from October 2013 to March 2014. All new patients who presented to the Clinic were included and details like their BMI, diagnosis and prescribed treatment were collected. Patients who were advised diet modifications were monitored for follow up visits.

Results: In the study period, 181 new patients presented to the clinic for sleep problems (140 Males/ 41 Females, Age 47.4±16.12). Of these 181, 125 patients were advised to see the dietitian for diet treatment and weight reduction by the sleep specialist. All these 125 patients were overweight or obese (48.8% – overweight, 45.6% – obese and 5.6% – extremely obese). 120 out of 125 patients (96%) presented to the initial diet counselling and only 26 of them (21.6%) presented to a follow up session. Others (94) quoted lack of time (55.3%) and being unable to follow the prescribed diet guidelines (44.7%) as reasons for not presenting for follow up.

Conclusion: A significant number of overweight and obese patients accept initial diet counselling as prescribed by the Physician. However, a significant number of them do not follow up quoting lack of time and inability to comply as the primary reasons. The results suggest a lack of knowledge among healthcare seekers towards the role of nutritional therapy for wellness and disease management.